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STATUS REPORT Dated |
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Although in vitro studies have shown that the lysosomal distribution of LDLderived cholesterol is defective in cultured cells of NP-C subjects, no unusual characteristics mark the plasma lipoprotein profiles. We aim to determine whether anomalies exist in vivo in the cellular distribution of newly synthesized, HDLderived or LDL-derived cholesterol under physiologic conditions in NP-C subjects. |
Report Not Yet Available | |
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PUBLICATIONS: http://www.jlr.org/cgi/reprint/38/12/2422.pdf |
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