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Fellowships Funded by the
NNPDF and CCNNPDF

(To see a listing of the Research Grants jointly sponsored by the NNPDF and CCNNPDF, click here.)

(To see a listing of the Clinical Research and Services funded by the NNPDF, click here.)

Item #


Date


Researcher


Project

Additional
Information

8 9/2011 -
9/2012

Andrew Munkacsi, Ph.D.
Sponsor: Stephen L. Sturley, Ph.D.
(Columbia University Medical Center;
New York, New York; USA)

Defining the molecular basis of HDAC inhibitors to treat murine, feline, and human models of NPC

$50,000
Jointly sponsored by NNPDF and CCNNPDF

In progress
(Updates to be posted every six months)
7 9/2010 -
9/2013
Dorothea Maetzel, Ph.D.
Sponsor: Rudolf Jaenisch, M.D.
(Whitehead Institute for Biomedical Research; Cambridge, Massachusetts; USA)

In Vitro modelling of Niemann-Pick type C Disease Using Patient-Specific Induced Pluripotent Stem Cells

$100,000
Jointly sponsored by NNPDF and CCNNPDF

Received third year extension of additional $50,000

In progress

April 2012 Update

Oct 2011 Update

April 2011 Update

Project Summary Sept 2010

6 9/2010 -
9/2013
Nicholas Cianciola, Ph.D.
Sponsor: Cathleen Carlin, Ph.D.
(School of Medicine, Case Western Reserve University; Cleveland, Ohio; USA)

Activation of an alternative cholesterol homeostatic mechanism in NPC

$100,000
Jointly sponsored by NNPDF and CCNNPDF

Received third year extension of additional $50,000

In progress

April 2012 Update

Oct 2011 Update

April 2011 Update

Project Summary Sept 2010

5 4/2010 -
4/2012
Fabrizio Vacca, Ph.D.
Sponsor: Professor Jean Gruenberg
(University of Geneva, Switzerland)
Analysis of cholesterol export from purified endosomes in NPC cellular models

$100,000
Jointly sponsored by NNPDF and CCNPDF
                   
In progress

Oct 2011 Update

April 2011
Update


Project Summary Sept 2010

4 9/2009 - 9/2011 Ian Williams, Ph.D.
Sponsor: Professor Fran Platt
(University of Oxford, UK)

Neurobiology of Purkinje Cells in NPC1

$100,000
Jointly sponsored by NNPDF and CCNNPDF
 
Completed

Oct 2011 Update

April 2011 Update

Project Summary Sept 2010

3

9/15/2004 - 9/14/2006

Nobutaka Ohgami, Ph.D.
Sponsor: T. Y. Chang, Ph.D.
(Dartmouth Medical School; Hanover, New Hampshire; USA)
(2)

Demonstration of NPC1 as a lipid binding protein in Vitro

$80,500

contract modified Jan 2006 to end 31/12/2007

Completed

More Details...

2

3/15/2003 - 3/14/2005

Heng-Ling Liou, Ph.D.
Sponsor: Peter Lobel, Ph.D.
(University of Medicine & Dentistry of New Jersey -Robert Wood Johnson Medical School; Piscataway, New Jersey, USA)
(2 years)

The Role of NPC2 (Niemann-Pick Disease Type C2) Protein in Lysosomal Cholesterol Trafficking

$80,500

Completed

More Details...

1

3/15/2003 - 3/14/2005

Amit Kumar Choudhury, Ph.D.
Sponsor: Richard E. Pagano, Ph.D.
(Mayo Clinic and Foundation; Rochester, Minnesota, USA)
(2 years)

Reduction of Lipid Accumulation in Niemann-Pick Fibroblasts by Modulation of Membrane Trafficking

$80,500

Completed

More Details...

 

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